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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2f50264e226d84dac957b5d230ed49bf853a9d8778d04c012ab501af2f0092c' 
  AND token = 'HCigsKLkR8caZ4+bfopADdY9WN2V3k7hmspDuLCwhQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}