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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64decf333e8b16b867e4ceafe5e12826757770219b87cc5cf98f36d5c406b229' 
  AND token = 'R2J4yJb5M6h3YtEmu3zenQVWIHgr5bMdOZc8zKMGNrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}