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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be412bb6b5b0c1b50277b95d8d48dd2fcd7767eec2fb6a4d74bb472f75a24a78' 
  AND token = 'MiQX0EwQMtwgvtP2jG3HWaNlm89LWpHMYETKVy5ZhUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}