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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '763ef4a23c5efa756444b2511e2e3512e94a4c2ad3fff0f83dc8ce181bf750a1' 
  AND token = 'XTqSbr+AKO+fEHIp/E6hPN3UdBoyfP4gjP9UL8KZ32I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}