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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764166d90568f24ee1c468fb4a841bd9baab62c5b785976b8242cdef43f378f7' 
  AND token = 'dfIhUOTl6+9otzz0GC+QWG3hE6Ho0Q0IbskxPeWzpgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}