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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e460826722ff889ee1c8189cbb2e7fb8cfbda8c10bd48a84e4c16699fd57fa89' 
  AND token = 'Km2DQmQXWBRt2Wwi9cuy0ijzR6lyOrLTmzmQO7o4sRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}