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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1c21f6717b0757dd5df496b629b7f5aaeb74693c33b27236d0dab04af21a25' 
  AND token = 'D9GvsjltWDqQD1aXAgrpLmvLpN2QYvK4X3OBmxDGHLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}