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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787735567721f7924865a87eb5558bdf353032ce0331a83b11006bd1065ec801' 
  AND token = 'rqalvCTrCSDUDjkPDEhwUC6cNqhsq5QDsb+gmMJ7iY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}