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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5eec8f8d0fea46845c5fff2f9e7b8c6c503ee1bb9df2e1f774b6f0f95b61de6' 
  AND token = 'RoUUjX49EWrg25B393AmZwMD3Fa3lzlScFEC3hefvA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}