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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00366bf76f59ce3f5441940caa957b5018bbeed0a94f34f1fee809f30b3393b1' 
  AND token = 'fk3P7ST9HAr4FePXPRECev+TkA0IPMxvXgWE0cKCY9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}