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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8738afb132f90a53f753aafebfa00390f263f768ae1265616d8ca270c8b0dacd' 
  AND token = 'wZ65k4nL05aRHBpsMOFVAMSEhnjAFbffaFeoEeDnTkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}