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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a20a195b265f5e342f249de287793a74ee5b9657a23ebc98e6804ebc366043' 
  AND token = 'VkPceIfTCP+Wh0kjncqjdBEGtWJn5ysw8u9JFLtihfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}