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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21402e4dda6721c629a012005b73ad852b9187a38ccffdfbc42016e4162dbc15' 
  AND token = 'N9OT0WvoFqVKcHSfCOcctxsMSCu/0/tpJl9W3P7p+0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}