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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fcb9c9877faa58188a48c252d1edef86a3fbe788e6806696e19f30b25c5c4a3' 
  AND token = 'OAhA9Z3qJnawnZvaJ2i2TB9kQEtjnkczZNDYmd4lXzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}