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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f39497525413efc491206a5f0b790cd0574971cf685c2e58937fde09e9dc4f' 
  AND token = 'vqdjK9Mt0EPnhielFMoUiZJkTbULr4E+n1MfilGulhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}