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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3635fedd63fa4fe01cdc4472b1170c54165b33c0f82e1ee4ab025119711859a5' 
  AND token = '4PTFe9IjKz/WEYYqrTd31DDjBd3Qc7XDOZxJbjUu+24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}