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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4ab5ff2e4fb7f6b9fdd8ba17ba791e61e4bc6b6e7e0b4d3164edb3d1cb4b48' 
  AND token = 'K3v3U7SDzLAn+/mh//dVLsThFSTjvbHdSYq5kQQ4m9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}