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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b72e2a0ab393b55fde0f15503a242e5f9a75a8a9bbc4612915980d4a3904630' 
  AND token = 'AG91lEoz53S7hW4n3fNOwr6/q8xx4S+n4YpmzQRQi5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}