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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aca08761f101713612d81a144225f2813eacb2b9dd69b387b89ec82c9cf7b84c' 
  AND token = 'FHVxHoXI+v+KX/TD67fH7FrQNaWY0fprXpFImPVWXU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}