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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20e8b1248d37abf93cc756df60d7a65da9940d005b37c3bdc16c96f46557500c' 
  AND token = '8+bEV7iK1LVpyOLfWn/R/tCl3fQpcbODKXJrzvmWd34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}