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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '820846c21765ef562598285736c0783890fdf88e0872a4bb77f61b4308028455' 
  AND token = '3+/YRHAyCj4zxiu9Wj9uiopVHs0CSZs0m2pDOTQAjYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}