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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b78b7a39e8d22922c9c03338c13bc235e7e0153e2314cb4fda17c5e41d7dd1' 
  AND token = 'EG0PA44DvMF9/5x21EEN0FVYkfVTXNTWHnDga8u91mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}