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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03cdd6648da625bf3301d1dd8d4c0211f22861a5febf8509c418e2777e9948cd' 
  AND token = 'fRtQ+9RVb+Ko2M0Q05cLoOT/TZQfnojKTtUHp8rrzlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}