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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ee0d268348bd36911251a40578c9ef6fc9c373a2f1272466294ae3ee6499ff' 
  AND token = 'ZtWdzxhNRC0k0cIY+sMTifrxDDk7RmANHJr3r/9cp28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}