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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37427400974b45119ec6e3e19d5ad8d43f053fc23aaf8b62b210c8e94618d8c2' 
  AND token = 'Jt8L7Nb/2GCe18Wz97DxeRGG/2Cm5HAsbXCjl11XLMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}