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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60271721d434ae206e9f3c8efb5e146b66375a0d1a36304f1fcbe865ae8cef5f' 
  AND token = 'zlAHeK6sdTAhuN/ZyE2usHIIU9CJuA3p0lpFD14YLp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}