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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b407592f317e6a900e7a23647a4ab1844f391aa967d5461c63aa6f8e1e4d1606' 
  AND token = 'umlcJckEHjRRULuTyk0GKVvI62jwCmdhyowwQtWo+48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}