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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c384dd08c1cd9006ee364bce18d113056b06da39f2fba3df46e1c7de12a9b2' 
  AND token = 'Hutw8Hl4h/FSjMq56O0BI40Os8DxTWt685uWC9r2T1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}