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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e3e94ef0341cc0853103dd75ed4172c2e0ba695b02bfd9dabc1022f8530c8c' 
  AND token = 'aJa1mgl7Gl8xlD7gZKR0k77TWsZhDFpysFCxewoWvz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}