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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2895b3c3fdcd3ceb665bd73063f51e19854d1c2d8a33ce96e0b6668c9a2ca246' 
  AND token = 'fpWrN1zvzb0h8rbh75D2yzksBgF/dfh9xyhdCn19p5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}