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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4202b4e0c77234278bba09aa71aeae4b9d825fd2d165d976ec755d1d28a8fb46' 
  AND token = 'wVFwt6fb6sC6B4eZIXllwF0B4TEHkzT7XwWqiOMW+R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}