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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd14559760428a3eb30e06034ffb9d190a3814f12c6ad3e8a47b3ae1af63c3878' 
  AND token = 'lyJYCQbuZ0jTGLmDhvLDmib7ZgQsJLx9dKkJOx9tnEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}