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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8526b647fbf932dda5f6757e05e51f238da1a8f062cf68f73001274c9b3c45' 
  AND token = 'dd8cOxUwm6Te7Q2Vx7jHHYkAHDt9VwZFplvrwPUlYoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}