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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26876c80b20acea5c1a52a494e4c4b97b9306f04e206b6f8727f64a4bc4a389d' 
  AND token = 'e0BwAVgtiYoznF76doN7EGWj1m4915pllkvLvzE3PJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}