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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '965f8e252e01bc9d943d187c075962528a8581c3cefe31d594bc3bd4cd17ed70' 
  AND token = 'v/NsquFL1anbpIREikca5o2nK+B/CdMODW7VJqdf824=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}