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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02187189e74679c2ee20914c56c8adbd59bca0fead4e6a9b71e3dac4e7516e60' 
  AND token = 'd3K1hq+zyxoDb0k09VypFAUUvOPxu5QesQxRUdLHh3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}