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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2fac9f5a0010180fe9114af0ca4b14d54cc5db1d5cdb86776e6ed98d6a2597' 
  AND token = 'nDIQBPt+kFR05XKqEzKY1lY1U+mS6xM0QJWC2L+zPEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}