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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91229d0d2f43fdda8e19747fcf7140ed5f34c7766505386d4e395e33fdb3f540' 
  AND token = 'OdJfW+QNh9Ywn0cSGMe9qiy6M+NNplgRAREYRxmiP8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}