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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21eeb21dc82b9f243c4923de34385a5ef07189b1387cedb089d84733f9d7e9f' 
  AND token = 'LMKgn7j5Hx0R/BrdDuWudoxnUbvxZILi06/lNJSJsPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}