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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4a4ffd4a822a3ba6998df85ad4aabea7e63799addcdcd8311c96ed6895a2f09' 
  AND token = 'xRHHdgcewykWmyTLsawd3IHUagHl65I+VDvphCCwkGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}