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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2326ec8379635f420917fa5b869bd6e3385e3b417337a6619c3116d0c9301281' 
  AND token = 'ZN1jYC9/df5bCNagxc5I+49f4u5Em3qgN2uthGuCUVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}