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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729dd14e5133c82fc5870844fb1dafa9715648f84280e2982df84246ef03df93' 
  AND token = '72zChfH1zAvk+IETRA36+ZsEFmHoE5vac/SttAIrNpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}