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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3372e89a49977a9ad80d31d5ed1538e2af6e16d1a4e7f76a79da0ffe2dc3f72' 
  AND token = 'cePwypXfBbypuGzDDhr69hhSM3cpqGV/Yc6rMKZRNoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}