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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd775ade095ddab77d71f976ec2348cdc3b01fc5424cce05ab05487cfd91bd971' 
  AND token = 'HRmy7Ph7DyUVM1FOiXliX1uxEEcd1b2bMdmaXwxL9Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}