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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c66060725ebce7aac9bea4e881fdea498def4796096ccd0aa09fd02ee794aa' 
  AND token = 'SPiKuq6v39BUpaEtP9vA/PLzdBs0TLuatcs+/YOUsHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}