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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b73daf4a878fc26b9b469b626ddbc14de708ee1dfe002785d930f73f9441262' 
  AND token = 'yJ1W9AQ3V06sYVnLu+RGCyru8Dt0N9OF2JdTKGZ6Mn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}