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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a1b73aa2baceaeccb3aad2fd3e506cb9b24cff762d7a5dad9f30e031f3a910' 
  AND token = 'Q3ofNmvjuxGN+VjXHEhAmy4j5PPZ/MEx0rEChm0c0Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}