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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb21acf1f3a05712cc9f6adf0ea6f466bd517a91c8efb3486e57cab58467aa4' 
  AND token = 'onFWpC5iN4ZvzO5/TjJ5IBtSs6ukkH0M44WxdCd5eas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}