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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b38d65b9a727457bf2291aad79846405e2ba453ff3859b7a781cab9f1d0f8bbf' 
  AND token = 'swn84whRymxym933D6rWzpCt429n8GNPdQSSrcfbJl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}