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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a581a0683f4814348c9ce2f5cc6d055e53afe8451fd23392146fe995c2c728f7' 
  AND token = 'wB9oMF1R085AMQgXVQxRwpag5npnB/ButyZoa2BfXUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}